Hassan Issafras Selected Research

gevokizumab

6/2011	Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice.
1/2011	XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases.

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Hassan Issafras Research Topics

Disease

3	Neoplasms (Cancer) 11/2021 - 10/2018
2	Hypoglycemia (Reactive Hypoglycemia) 07/2014 - 01/2014
2	Metabolic Diseases (Metabolic Disease) 07/2014 - 01/2011
1	Exanthema (Rash) 11/2021
1	Head and Neck Neoplasms (Head and Neck Cancer) 11/2021
1	Colorectal Neoplasms (Colorectal Cancer) 11/2021
1	Weight Gain 12/2016
1	Hyperinsulinism (Hyperinsulinemia) 07/2014
1	Insulin Resistance 01/2014
1	Insulinoma 01/2014
1	Congenital Hyperinsulinism 01/2014
1	Atherosclerotic Plaque (Atheroma) 06/2011
1	Cardiovascular Diseases (Cardiovascular Disease) 06/2011
1	Atherosclerosis 06/2011
1	Inflammation (Inflammations) 01/2011
1	Peritonitis 01/2011
1	Gout 01/2011
1	Obesity 01/2011

Drug/Important Bio-Agent (IBA)

3	Monoclonal AntibodiesIBA 01/2021 - 06/2011
2	Insulin (Novolin)FDA Link 07/2014 - 01/2014
2	gevokizumabIBA 06/2011 - 01/2011
1	Polysaccharides (Glycans)IBA 11/2021
1	Cetuximab (Erbitux)FDA Link 11/2021
1	HLX07IBA 11/2021
1	Programmed Cell Death 1 ReceptorIBA 01/2021
1	pembrolizumabIBA 01/2021
1	NivolumabIBA 01/2021
1	Immunoglobulin G (IgG)IBA 01/2021
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021
1	CEACAM1 ProteinIBA 10/2018
1	Detergents (Detergent)IBA 12/2016
1	LigandsIBA 07/2014
1	Insulin ReceptorIBA 01/2014
1	Dihydrotachysterol (AT 10)IBA 01/2014
1	Peptide Hydrolases (Proteases)FDA Link 06/2011
1	Apolipoproteins E (ApoE)IBA 06/2011
1	ApolipoproteinsIBA 06/2011
1	Biomarkers (Surrogate Marker)IBA 06/2011
1	CytokinesIBA 06/2011
1	Interleukin-1beta (Interleukin 1 beta)IBA 06/2011
1	Pharmaceutical PreparationsIBA 01/2011

Therapy/Procedure

2	Immunotherapy 01/2021 - 10/2018
1	Intraperitoneal Injections 01/2014
1	Therapeutics 01/2014